Stand-up comedian, actor, and television host Bob Saget has died at the age of 65.

According to the Orange County Sheriff’s Office in Florida, deputies were called to the Ritz-Carlton in Orlando on Sunday after an unresponsive man was found in a hotel room.

The sheriff’s office said in a statement, “The man was identified as Robert Saget and pronounced deceased on scene. Detectives found no signs of foul play or drug use in this case,” according to NPR.

Saget was on tour and had done a show near Jacksonville a day earlier, according to the news outlet.

He was famous for his acting roles, including Danny Tanner on the ABC sitcom Full House and its Netflix sequel Fuller House. His acting roles also include the voice of narrator Ted Mosby on the CBS sitcom How I Met Your Mother.

Saget was the original host of the ABC series America’s Funniest Home Videos from 1989 to 1997. He was also known for his adult-oriented stand-up comedy. His 2014 album That’s What I’m Talkin’ About was nominated for the Grammy Award for Best Comedy Album.

His friends and co-stars paid tribute on social media.

John Stamos, a Full House co-star, wrote, “I am broken. I am gutted. I am in complete and utter shock. I will never ever have another friend like him. I love you so much Bobby.”

Writer and producer Norman Lear called Saget a close friend who “was as lovely a human as he was funny. And to my mind, he was hilarious.”

How I Met Your Mother co-creator Craig Thomas said, “I don’t even know what to say about Bob Saget. I loved him and was so lucky to work with someone so funny, soulful and kind.”

Born on May 17, 1956, in Philadelphia, Saget attended Temple University’s film school, where he created Through Adam’s Eyes, a black-and-white film.

He also advocated for people suffering from scleroderma, an autoimmune disease that involves the hardening and tightening of the skin and connective tissues. His sister, Gay Saget, died of the condition in her 40s.